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Immune responses, vaccination and antibody technologies

Disease, immunity and health · Lesson 3 of 5

Lesson 3 of 5

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Lesson 3 of 5 · Disease, immunity and health

Immune responses, vaccination and antibody technologies

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Explain non-specific defence mechanisms, including physical and chemical barriers, phagocytosis, inflammation and other innate responses that reduce pathogen entry or survival.
Describe the roles of lymphocytes, antigen-presenting cells and clonal selection in the specific immune response, using the terms antigen, antibody, plasma cell, memory cell and phagocyte accurately.

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Compare primary and secondary immune responses and apply this to the biological basis of long-term immunity and the effectiveness of vaccination programmes.

Evaluate vaccination in terms of individual protection, herd immunity, risks, limitations, pathogen variation and ethical or public-health considerations.

Explain the production and use of monoclonal antibodies or other antibody technologies in diagnosis, targeted therapy, imaging, pregnancy testing and research, and evaluate their benefits and limitations.

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